{"id":392,"date":"2021-11-25T00:21:17","date_gmt":"2021-11-24T23:21:17","guid":{"rendered":"https:\/\/www.gastroenterology-info.at\/?page_id=392"},"modified":"2022-08-17T18:01:38","modified_gmt":"2022-08-17T16:01:38","slug":"studiendaten","status":"publish","type":"page","link":"https:\/\/www.gastroenterology-info.at\/studiendaten\/","title":{"rendered":"Studiendaten"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-image:linear-gradient(20deg, #891b8a 0%,#3b1442 100%);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-align-content-center\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-top:15px;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:rgba(255,255,255,0.25);border-top-width:1px;\"><\/div><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-1{margin-top:10px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-1{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-one\" style=\"font-size:80px;margin-top:10px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h1 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"font-family:&quot;Knockout-50Welterweight&quot;;font-weight:400;margin:0;font-size:1em;color:#ffffff;--fontSize:80;line-height:1.16;\"><h1>STUDIENDATEN<\/h1><\/h1><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start fusion-flex-align-content-center\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-0 fusion_builder_column_inner_1_1 1_1 fusion-flex-column fusion-no-small-visibility fusion-no-medium-visibility\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-row\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div ><style type=\"text\/css\">.fusion-button.button-1 .fusion-button-text, .fusion-button.button-1 i {color:#ffffff;}.fusion-button.button-1 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-1:hover .fusion-button-text, .fusion-button.button-1:hover i,.fusion-button.button-1:focus .fusion-button-text, .fusion-button.button-1:focus i,.fusion-button.button-1:active .fusion-button-text, .fusion-button.button-1:active{color:rgba(255,255,255,0.5);}.fusion-button.button-1:hover .fusion-button-icon-divider, .fusion-button.button-1:hover .fusion-button-icon-divider, .fusion-button.button-1:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.5);}.fusion-button.button-1:hover, .fusion-button.button-1:focus, .fusion-button.button-1:active{border-color:#ffffff;border-width:1px;}.fusion-button.button-1 {border-color:#ffffff;border-width:1px;border-radius:4px;}.fusion-button.button-1{background: rgba(232,232,232,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(214,214,214,0) ), to( rgba(232,232,232,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(214,214,214,0), rgba(232,232,232,0) );}.fusion-button.button-1:hover,.button-1:focus,.fusion-button.button-1:active{background: rgba(214,214,214,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(232,232,232,0) ), to( rgba(214,214,214,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(232,232,232,0), rgba(214,214,214,0) );}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-1 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"#klinische-studien\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Klinische Studien<\/span><\/a><\/div><div ><style type=\"text\/css\">.fusion-button.button-2 .fusion-button-text, .fusion-button.button-2 i {color:#ffffff;}.fusion-button.button-2 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-2:hover .fusion-button-text, .fusion-button.button-2:hover i,.fusion-button.button-2:focus .fusion-button-text, .fusion-button.button-2:focus i,.fusion-button.button-2:active .fusion-button-text, .fusion-button.button-2:active{color:rgba(255,255,255,0.5);}.fusion-button.button-2:hover .fusion-button-icon-divider, .fusion-button.button-2:hover .fusion-button-icon-divider, .fusion-button.button-2:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.5);}.fusion-button.button-2:hover, .fusion-button.button-2:focus, .fusion-button.button-2:active{border-color:#ffffff;border-width:1px;}.fusion-button.button-2 {border-color:#ffffff;border-width:1px;border-radius:4px;}.fusion-button.button-2{background: rgba(232,232,232,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(214,214,214,0) ), to( rgba(232,232,232,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(214,214,214,0), rgba(232,232,232,0) );}.fusion-button.button-2:hover,.button-2:focus,.fusion-button.button-2:active{background: rgba(214,214,214,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(232,232,232,0) ), to( rgba(214,214,214,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(232,232,232,0), rgba(214,214,214,0) );}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-2 fusion-button-default-span fusion-button-default-type\" target=\"_self\" href=\"#real-world-evidence\"><span class=\"fusion-button-text\">Real World Evidence<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-0{width:100% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-0{width:100% !important;order : 0;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-0{width:100% !important;order : 0;}.fusion-builder-nested-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:100% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-1{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;min-height:475px;}@media only screen and (max-width:640px) {.fusion-body .fusion-flex-container.fusion-builder-row-1{ min-height:350px;}}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: #eedded;background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"klinische-studien\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-2{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-2{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-text fusion-title-size-two headline-2\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h2 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:55;line-height:1;\"><h2>KLINISCHE STUDIEN<\/h2><\/h2><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-3{margin-top:25px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-3{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-three headline-3\" style=\"margin-top:25px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h3 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:30;line-height:1.2;\"><h3>GEMINI<\/h3><\/h3><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-1 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-1\"><p><strong>Wirksamkeit und Sicherheit der Induktions- und Erhaltungstherapie mit der intraven\u00f6sen Formulierung von Vedolizumab wurden im GEMINI Studien Programm evaluiert.<\/strong><\/p>\n<p>GEMINI 1 war Colitis ulcerosa Patienten gewidmet, GEMINI 2 und 3 Patienten mit Morbus Crohn. Dar\u00fcber hinaus wurde die Langzeitsicherheit von Vedolizumab in der GEMINI LTS (Long Term Safety) Studie untersucht.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-1{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-1{width:50% !important;order : 0;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-1{width:100% !important;order : 0;}.fusion-builder-nested-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-2 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-2{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-2{width:50% !important;order : 0;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-2{width:100% !important;order : 0;}.fusion-builder-nested-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-3 fusion_builder_column_inner_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-4{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-4{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:20;--minFontSize:20px;line-height:1.36;\"><h4>Vollpublikation GEMINI 1<\/h4><\/h4><\/div><div class=\"fusion-text fusion-text-2\" style=\"font-size:13px;\"><p><em>Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis, Brian G. Feagan et al, New England Journal of Medicine 2013<\/em><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-3 .fusion-button-text, .fusion-button.button-3 i {color:#ffffff;}.fusion-button.button-3 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-3:hover .fusion-button-text, .fusion-button.button-3:hover i,.fusion-button.button-3:focus .fusion-button-text, .fusion-button.button-3:focus i,.fusion-button.button-3:active .fusion-button-text, .fusion-button.button-3:active{color:rgba(255,255,255,0.64);}.fusion-button.button-3:hover .fusion-button-icon-divider, .fusion-button.button-3:hover .fusion-button-icon-divider, .fusion-button.button-3:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-3:hover, .fusion-button.button-3:focus, .fusion-button.button-3:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-3 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-3{background: #891b8a;}.fusion-button.button-3:hover,.button-3:focus,.fusion-button.button-3:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-3 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1215734\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-3{width:25% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-3{width:25% !important;order : 0;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {margin-right : 7.68%;margin-left : 7.68%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-3{width:100% !important;order : 0;}.fusion-builder-nested-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-4 fusion_builder_column_inner_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-5{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-5{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:20;--minFontSize:20px;line-height:1.36;\"><h4>Vollpublikation GEMINI 2<\/h4><\/h4><\/div><div class=\"fusion-text fusion-text-3\" style=\"font-size:13px;\"><p><em>Vedolizumab as Induction and Maintenance Therapy for Crohn\u00b4s Disease, William J. Sandborn et al, New England Journal of Medicine 2013<\/em><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-4 .fusion-button-text, .fusion-button.button-4 i {color:#ffffff;}.fusion-button.button-4 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-4:hover .fusion-button-text, .fusion-button.button-4:hover i,.fusion-button.button-4:focus .fusion-button-text, .fusion-button.button-4:focus i,.fusion-button.button-4:active .fusion-button-text, .fusion-button.button-4:active{color:rgba(255,255,255,0.64);}.fusion-button.button-4:hover .fusion-button-icon-divider, .fusion-button.button-4:hover .fusion-button-icon-divider, .fusion-button.button-4:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-4:hover, .fusion-button.button-4:focus, .fusion-button.button-4:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-4 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-4{background: #891b8a;}.fusion-button.button-4:hover,.button-4:focus,.fusion-button.button-4:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-4 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1215739\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-4{width:25% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-4{width:25% !important;order : 0;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {margin-right : 7.68%;margin-left : 7.68%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-4{width:100% !important;order : 0;}.fusion-builder-nested-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-5 fusion_builder_column_inner_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-6{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-6{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-6 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:20;--minFontSize:20px;line-height:1.36;\"><h4>Vollpublikation GEMINI 3<\/h4><\/h4><\/div><div class=\"fusion-text fusion-text-4\" style=\"font-size:13px;\"><p><em>Effects of Vedolizumab Induction Therapy for Patients With Crohn\u2019s Disease in Whom Tumor Necrosis Factor Antagonist Treatment Failed, Bruce E. Sands, Gastroenterology 2014<\/em><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-5 .fusion-button-text, .fusion-button.button-5 i {color:#ffffff;}.fusion-button.button-5 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-5:hover .fusion-button-text, .fusion-button.button-5:hover i,.fusion-button.button-5:focus .fusion-button-text, .fusion-button.button-5:focus i,.fusion-button.button-5:active .fusion-button-text, .fusion-button.button-5:active{color:rgba(255,255,255,0.64);}.fusion-button.button-5:hover .fusion-button-icon-divider, .fusion-button.button-5:hover .fusion-button-icon-divider, .fusion-button.button-5:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-5:hover, .fusion-button.button-5:focus, .fusion-button.button-5:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-5 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-5{background: #891b8a;}.fusion-button.button-5:hover,.button-5:focus,.fusion-button.button-5:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-5 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.gastrojournal.org\/article\/S0016-5085(14)00656-8\/fulltext\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-5{width:25% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-5{width:25% !important;order : 0;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {margin-right : 7.68%;margin-left : 7.68%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-5{width:100% !important;order : 0;}.fusion-builder-nested-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-6 fusion_builder_column_inner_1_4 1_4 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-7{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-7{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-7 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:20;--minFontSize:20px;line-height:1.36;\"><h4>Vollpublikation GEMINI LTS<\/h4><\/h4><\/div><div class=\"fusion-text fusion-text-5\" style=\"font-size:13px;\"><p><em>Long-term safety of vedolizumab for inflammatory bowel disease, Edward V. Loftus, Alimentary Pharmacology and Therapeutics 2020<\/em><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-6 .fusion-button-text, .fusion-button.button-6 i {color:#ffffff;}.fusion-button.button-6 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-6:hover .fusion-button-text, .fusion-button.button-6:hover i,.fusion-button.button-6:focus .fusion-button-text, .fusion-button.button-6:focus i,.fusion-button.button-6:active .fusion-button-text, .fusion-button.button-6:active{color:rgba(255,255,255,0.64);}.fusion-button.button-6:hover .fusion-button-icon-divider, .fusion-button.button-6:hover .fusion-button-icon-divider, .fusion-button.button-6:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-6:hover, .fusion-button.button-6:focus, .fusion-button.button-6:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-6 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-6{background: #891b8a;}.fusion-button.button-6:hover,.button-6:focus,.fusion-button.button-6:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-6 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/apt.16060\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-6{width:25% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 7.68%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 7.68%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-6{width:25% !important;order : 0;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {margin-right : 7.68%;margin-left : 7.68%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-6{width:100% !important;order : 0;}.fusion-builder-nested-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-8{margin-top:25px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-8{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-8 fusion-sep-none fusion-title-text fusion-title-size-three headline-3\" style=\"margin-top:25px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h3 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:30;line-height:1.2;\">VISIBLE<\/h3><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-7 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-6\"><p><strong>Wirksamkeit und Sicherheit der Erhaltungstherapie mit der subkutanen Formulierung von Vedolizumab wurde im VISIBLE Studien Programm evaluiert.<\/strong><\/p>\n<p>Die VISIBLE-Studien untersuchten die Wirksamkeit und Sicherheit der subkutanen Formulierung von Vedolizumab zur Erhaltungstherapie bei erwachsenen Patienten mit mittelschwerer bis schwerer aktiver Colitis ulcerosa bzw. mittelschwerem bis schwerem aktiven Morbus Crohn.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-7{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-7{width:50% !important;order : 0;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-7{width:100% !important;order : 0;}.fusion-builder-nested-column-7 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-8 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-8{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-8{width:50% !important;order : 0;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-8{width:100% !important;order : 0;}.fusion-builder-nested-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-9 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-7\"><h4>Vollpublikation VISIBLE 1<\/h4>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-7 .fusion-button-text, .fusion-button.button-7 i {color:#ffffff;}.fusion-button.button-7 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-7:hover .fusion-button-text, .fusion-button.button-7:hover i,.fusion-button.button-7:focus .fusion-button-text, .fusion-button.button-7:focus i,.fusion-button.button-7:active .fusion-button-text, .fusion-button.button-7:active{color:rgba(255,255,255,0.64);}.fusion-button.button-7:hover .fusion-button-icon-divider, .fusion-button.button-7:hover .fusion-button-icon-divider, .fusion-button.button-7:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-7:hover, .fusion-button.button-7:focus, .fusion-button.button-7:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-7 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-7{background: #891b8a;}.fusion-button.button-7:hover,.button-7:focus,.fusion-button.button-7:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-7 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.gastrojournal.org\/article\/S0016-5085(19)41247-X\/fulltext?referrer=https:\/\/www.gastrojournal.org\/\" style=\"margin-top:16px;margin-bottom:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><div class=\"fusion-text fusion-text-8\" style=\"font-size:13px;\"><p><i>Sandborn WJ et al. Efficacy and Safety of Vedolizumab Subcutaneous Formulation in a Randomized Trial of Patients With Ulcerative Colitis.Gastroenterology. 2\/2020;158(3):562-572.e12<\/i><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-8 .fusion-button-text, .fusion-button.button-8 i {color:#891b8a;}.fusion-button.button-8 .fusion-button-icon-divider{border-color:#891b8a;}.fusion-button.button-8:hover .fusion-button-text, .fusion-button.button-8:hover i,.fusion-button.button-8:focus .fusion-button-text, .fusion-button.button-8:focus i,.fusion-button.button-8:active .fusion-button-text, .fusion-button.button-8:active{color:rgba(137,27,138,0.5);}.fusion-button.button-8:hover .fusion-button-icon-divider, .fusion-button.button-8:hover .fusion-button-icon-divider, .fusion-button.button-8:active .fusion-button-icon-divider{border-color:rgba(137,27,138,0.5);}.fusion-button.button-8:hover, .fusion-button.button-8:focus, .fusion-button.button-8:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-8 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-8{background: rgba(232,232,232,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(214,214,214,0) ), to( rgba(232,232,232,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(214,214,214,0), rgba(232,232,232,0) );}.fusion-button.button-8:hover,.button-8:focus,.fusion-button.button-8:active{background: rgba(214,214,214,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(232,232,232,0) ), to( rgba(214,214,214,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(232,232,232,0), rgba(214,214,214,0) );}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-8 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"http:\/\/www.gastroenterology-info.at\/wp-content\/uploads\/2021\/12\/VISIBLE_speaker-slide-kit_2021.pdf\"><span class=\"fusion-button-text\">Vortragsslides zur Weiterverwendung<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-9{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-9{width:50% !important;order : 0;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-9{width:100% !important;order : 0;}.fusion-builder-nested-column-9 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-10 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-9\"><h4>Vollpublikation VISIBLE 2<\/h4>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-9 .fusion-button-text, .fusion-button.button-9 i {color:#ffffff;}.fusion-button.button-9 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-9:hover .fusion-button-text, .fusion-button.button-9:hover i,.fusion-button.button-9:focus .fusion-button-text, .fusion-button.button-9:focus i,.fusion-button.button-9:active .fusion-button-text, .fusion-button.button-9:active{color:rgba(255,255,255,0.64);}.fusion-button.button-9:hover .fusion-button-icon-divider, .fusion-button.button-9:hover .fusion-button-icon-divider, .fusion-button.button-9:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-9:hover, .fusion-button.button-9:focus, .fusion-button.button-9:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-9 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-9{background: #891b8a;}.fusion-button.button-9:hover,.button-9:focus,.fusion-button.button-9:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-9 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/academic.oup.com\/ecco-jcc\/advance-article\/doi\/10.1093\/ecco-jcc\/jjab133\/6353295\" style=\"margin-top:16px;margin-bottom:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><div class=\"fusion-text fusion-text-10\" style=\"font-size:13px;\"><p><i>Vermeire S et al. Efficacy and Safety of Subcutaneous Vedolizumab in Patients With Moderately to Severely Active Crohn\u2019s Disease: Results From the VISIBLE 2 Randomised Trial,\u00a0Journal of Crohn&#8217;s and Colitis, 2021<\/i><\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-10 .fusion-button-text, .fusion-button.button-10 i {color:#891b8a;}.fusion-button.button-10 .fusion-button-icon-divider{border-color:#891b8a;}.fusion-button.button-10:hover .fusion-button-text, .fusion-button.button-10:hover i,.fusion-button.button-10:focus .fusion-button-text, .fusion-button.button-10:focus i,.fusion-button.button-10:active .fusion-button-text, .fusion-button.button-10:active{color:rgba(137,27,138,0.5);}.fusion-button.button-10:hover .fusion-button-icon-divider, .fusion-button.button-10:hover .fusion-button-icon-divider, .fusion-button.button-10:active .fusion-button-icon-divider{border-color:rgba(137,27,138,0.5);}.fusion-button.button-10:hover, .fusion-button.button-10:focus, .fusion-button.button-10:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-10 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-10{background: rgba(232,232,232,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(214,214,214,0) ), to( rgba(232,232,232,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(214,214,214,0), rgba(232,232,232,0) );}.fusion-button.button-10:hover,.button-10:focus,.fusion-button.button-10:active{background: rgba(214,214,214,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(232,232,232,0) ), to( rgba(214,214,214,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(232,232,232,0), rgba(214,214,214,0) );}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-10 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.takeda.com\/4ab30a\/siteassets\/de-at\/home\/hcps\/restricted\/entyvio\/wissenschaftsupdate\/visible12\/visible-2_vermeire_ecco_2020.pptx\"><span class=\"fusion-button-text\">Vortragsslides zur Weiterverwendung<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-10{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-10{width:50% !important;order : 0;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-10{width:100% !important;order : 0;}.fusion-builder-nested-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-9{margin-top:25px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-9{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-9 fusion-sep-none fusion-title-text fusion-title-size-three headline-3\" style=\"margin-top:25px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h3 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:30;line-height:1.2;\">VARSITY<\/h3><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-11 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-11\"><p><strong>VARSITY \u2013 eine Head-to-Head-Studie zweier Biologika (Adalimumab und Vedolizumab) in Patienten mit moderater-schwerer Colitis ulcerosa <span class=\"Apple-converted-space\">\u00a0<\/span><\/strong><\/p>\n<p>Vedolizumab war Adalimumab bei klinischer Remission und Mukosaheilung in Woche 52 bei Patienten mit mittelschwerer bis schwerer Colitis ulcerosa \u00fcberlegen<\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-11 .fusion-button-text, .fusion-button.button-11 i {color:#891b8a;}.fusion-button.button-11 .fusion-button-icon-divider{border-color:#891b8a;}.fusion-button.button-11:hover .fusion-button-text, .fusion-button.button-11:hover i,.fusion-button.button-11:focus .fusion-button-text, .fusion-button.button-11:focus i,.fusion-button.button-11:active .fusion-button-text, .fusion-button.button-11:active{color:rgba(137,27,138,0.5);}.fusion-button.button-11:hover .fusion-button-icon-divider, .fusion-button.button-11:hover .fusion-button-icon-divider, .fusion-button.button-11:active .fusion-button-icon-divider{border-color:rgba(137,27,138,0.5);}.fusion-button.button-11:hover, .fusion-button.button-11:focus, .fusion-button.button-11:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-11 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-11{background: rgba(232,232,232,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(214,214,214,0) ), to( rgba(232,232,232,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(214,214,214,0), rgba(232,232,232,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(214,214,214,0), rgba(232,232,232,0) );}.fusion-button.button-11:hover,.button-11:focus,.fusion-button.button-11:active{background: rgba(214,214,214,0);\n\t\t\t\t\t\t\tbackground-image: -webkit-gradient( linear, left bottom, left top, from( rgba(232,232,232,0) ), to( rgba(214,214,214,0) ) );\n\t\t\t\t\t\t\tbackground-image: -webkit-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:   -moz-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image:     -o-linear-gradient( bottom, rgba(232,232,232,0), rgba(214,214,214,0) );\n\t\t\t\t\t\t\tbackground-image: linear-gradient( to top, rgba(232,232,232,0), rgba(214,214,214,0) );}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-11 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.takeda.com\/4ab307\/siteassets\/de-at\/home\/hcps\/restricted\/entyvio\/wissenschaftsupdate\/varsity2019\/2019-11_slidekit_varsity_sands_nejm_german.pptx\"><span class=\"fusion-button-text\">Vortragsslides zur Weiterverwendung<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-11{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-11{width:50% !important;order : 0;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-11{width:100% !important;order : 0;}.fusion-builder-nested-column-11 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-12 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-10{margin-top:10px!important; margin-right:0px!important;margin-bottom:15px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-10{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-10 fusion-sep-none fusion-title-text fusion-title-size-four\" style=\"margin-top:10px;margin-right:0px;margin-bottom:15px;margin-left:0px;\"><h4 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:20;--minFontSize:20px;line-height:1.36;\"><h4>Vollpublikation VARSITY<\/h4><\/h4><\/div><div ><style type=\"text\/css\">.fusion-button.button-12 .fusion-button-text, .fusion-button.button-12 i {color:#ffffff;}.fusion-button.button-12 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-12:hover .fusion-button-text, .fusion-button.button-12:hover i,.fusion-button.button-12:focus .fusion-button-text, .fusion-button.button-12:focus i,.fusion-button.button-12:active .fusion-button-text, .fusion-button.button-12:active{color:rgba(255,255,255,0.64);}.fusion-button.button-12:hover .fusion-button-icon-divider, .fusion-button.button-12:hover .fusion-button-icon-divider, .fusion-button.button-12:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-12:hover, .fusion-button.button-12:focus, .fusion-button.button-12:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-12 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-12{background: #891b8a;}.fusion-button.button-12:hover,.button-12:focus,.fusion-button.button-12:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-12 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1905725\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-12{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-12{width:50% !important;order : 0;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-12{width:100% !important;order : 0;}.fusion-builder-nested-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:100% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-2{ padding-top : 70px;margin-top : 0px;padding-right : 0px;padding-bottom : 70px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"real-world-evidence\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-11{margin-top:10px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-11{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-11 fusion-sep-none fusion-title-text fusion-title-size-two headline-2\" style=\"margin-top:10px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h2 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:55;line-height:1;\"><h2>REAL WORLD EVIDENCE<\/h2><\/h2><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-13 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-12{margin-top:25px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-12{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-12 fusion-sep-none fusion-title-text fusion-title-size-three headline-3\" style=\"margin-top:25px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h3 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:30;line-height:1.2;\"><h3>EVOLVE<\/h3><\/h3><\/div><div class=\"fusion-text fusion-text-12\"><p>EVOLVE ist ein retrospektiver Chart-Review mit \u00fcber die 1.000 Patienten aus 37 Zentren in 3 L\u00e4ndern (Kanada, USA, Griechenland). Er untersucht die Langzeitergebnisse bei bio-naiven CED-Patienten unter Vedolizumab- oder Anti-TNF-\u03b1- Therapie mit Colitis ulcerosa und Morbus Crohn in Bezug auf Wirksamkeit, Behandlungsalgorithmus, Ressourcennutzung des Gesundheitssystems sowie Sicherheit.<\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-13 .fusion-button-text, .fusion-button.button-13 i {color:#ffffff;}.fusion-button.button-13 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-13:hover .fusion-button-text, .fusion-button.button-13:hover i,.fusion-button.button-13:focus .fusion-button-text, .fusion-button.button-13:focus i,.fusion-button.button-13:active .fusion-button-text, .fusion-button.button-13:active{color:rgba(255,255,255,0.64);}.fusion-button.button-13:hover .fusion-button-icon-divider, .fusion-button.button-13:hover .fusion-button-icon-divider, .fusion-button.button-13:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-13:hover, .fusion-button.button-13:focus, .fusion-button.button-13:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-13 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-13{background: #891b8a;}.fusion-button.button-13:hover,.button-13:focus,.fusion-button.button-13:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-13 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8495488\/\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-13{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-13{width:50% !important;order : 0;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-13{width:100% !important;order : 0;}.fusion-builder-nested-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-14 fusion_builder_column_inner_1_2 1_2 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">@media only screen and (max-width:1024px) {.fusion-title.fusion-title-13{margin-top:25px!important; margin-right:0px!important;margin-bottom:25px!important;margin-left:0px!important;}}@media only screen and (max-width:640px) {.fusion-title.fusion-title-13{margin-top:10px!important; margin-right:0px!important;margin-bottom:10px!important; margin-left:0px!important;}}<\/style><div class=\"fusion-title title fusion-title-13 fusion-sep-none fusion-title-text fusion-title-size-three headline-3\" style=\"margin-top:25px;margin-right:0px;margin-bottom:25px;margin-left:0px;\"><h3 class=\"title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:30;line-height:1.2;\">VICTORY<\/h3><\/div><div class=\"fusion-text fusion-text-13\"><p>Das VICTORY Konsortium ist eine multizentrische, nord-amerikanische Forschungsgruppe. Die Zentren sind auf CED-Patienten spezialisiert. Bei dieser Publikation des VICTORY Konsortiums handelt es sich um einen retrospektiven Chart-Review mit 1.266 Patienten (659 mit Vedolizumab, 302 Adalimumab\/Goliumamab, 305 Infliximab) aus den USA, der die Wirksamkeit und Sicherheit von Vedolizumab im Vergleich zu Anti-TNF-\u03b1 bei Patienten mit Morbus Crohn untersucht. In der Vedolizumab-Kohorte waren \u00fcber 90 % der Patienten mit Anti-TNF-\u03b1 vorbehandelt.<\/p>\n<\/div><div ><style type=\"text\/css\">.fusion-button.button-14 .fusion-button-text, .fusion-button.button-14 i {color:#ffffff;}.fusion-button.button-14 .fusion-button-icon-divider{border-color:#ffffff;}.fusion-button.button-14:hover .fusion-button-text, .fusion-button.button-14:hover i,.fusion-button.button-14:focus .fusion-button-text, .fusion-button.button-14:focus i,.fusion-button.button-14:active .fusion-button-text, .fusion-button.button-14:active{color:rgba(255,255,255,0.64);}.fusion-button.button-14:hover .fusion-button-icon-divider, .fusion-button.button-14:hover .fusion-button-icon-divider, .fusion-button.button-14:active .fusion-button-icon-divider{border-color:rgba(255,255,255,0.64);}.fusion-button.button-14:hover, .fusion-button.button-14:focus, .fusion-button.button-14:active{border-color:rgba(137,27,138,0.5);border-width:1px;}.fusion-button.button-14 {border-color:#891b8a;border-width:1px;border-radius:4px;}.fusion-button.button-14{background: #891b8a;}.fusion-button.button-14:hover,.button-14:focus,.fusion-button.button-14:active{background: rgba(135,0,137,0.64);}<\/style><a class=\"fusion-button button-flat fusion-button-default-size button-custom button-14 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7496810\/\" style=\"margin-right:16px;\"><span class=\"fusion-button-text\">Publikation ansehen<\/span><\/a><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-nested-column-14{width:50% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-nested-column-14{width:50% !important;order : 0;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-nested-column-14{width:100% !important;order : 0;}.fusion-builder-nested-column-14 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-2{width:100% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:640px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-3{ padding-top : 70px;margin-top : 0px;padding-right : 0px;padding-bottom : 70px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;width:100%;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"border-color:#e2e2e2;border-top-width:1px;\"><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-3{width:100% !important;margin-top : 0px;margin-bottom : 20px;}.fusion-builder-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only 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